Moein Kermanizadeh Tavakoli

Multimodal assessment of retinal function in late-stage glaucoma

I began my doctorate in December 2024 at Otto von Guericke University Magdeburg’s Visual Processing Laboratory under the guidance of Professor Michael Hoffmann, and Dr. Khaldoon Al-Nosairy enabled the daily research work. 

Personal Background and Interest

With a foundational background in both artificial intelligence and medicine in the application to the healthcare sector, I am excited about merging the two disciplines for the project. My region of aspiration is that my research will go further than being one more publication to the existing body of glaucoma literature and, instead, be an inspiration towards improved patient care. In addition, I am excited about being intellectually stimulated and rewarded by academia and achieving a consistent progression through every dataset.

Aim of the project

The objective of my PhD research is to describe the development of functional, vascular, and structural deficits in advanced glaucoma, as well as the development of a diagnostic tool for disease classification. The primary goal is to establish measurable parameters for tracking disease progression and, ultimately, guide possible future restorative treatment.

Current activities/Accomplishments

To achieve this objective, I take a multimodal approach that combines dynamic vessel analysis, perimetry, and non-invasive electrophysiology. This thorough assessment aims to monitor the progression of glaucoma-associated changes in retinal function. 

By combining these techniques, I aim to determine the diagnostic and prognostic significance of retinal microvascular defects, thereby creating a valid method of disease monitoring. During my PhD study, I will also acquire additional experience in two temporary assignments:

1. University of Groningen (UMCG), the Netherlands: I will be visiting Nomdo Jansonius for six months, investigating novel methods of glaucoma progression evaluation and prediction. 

2. Heidelberg Engineering, Germany: I will strive for the implementation of advanced retinal imaging technologies, advancing the interface between research endeavors and routine clinical applications.